In Harley's case, the lipoic acid supplement was used in combination with L-carnitine, Life Extension Mix, DHEA and a high-protein, human-grade diet. But it has no regulatory authority itself, it does not test pet food, and it does not issue any kind of certificate that a pet food is "complete and balanced." Ratings based on results of the 2021 and earlier ConsumerLab.com surveys of supplement users. The vet decided that Jack needed an intensive program starting with N-acetylcysteine (NAC). AAFCO makes no secret of the fact that it wants to cooperate with, not regulate, members of the pet food industry-an industry made up of rendering plants; manufacturers of vitamin premixes and flavorings; and multinational corporations. The dashboard displays a dry matter protein reading of 27%, a fat level of 20% and estimated carbohydrates of about 45%. Our newest formulation of FLORASSIST® GI targets unwanted bacteria with a novel bacteriophage blend while delivering a blend of seven healthy probiotic strains for digestive health support. We can't answer those questions, but we suspect that many vet bills are traceable to poor nutrition. Iams tried to argue that its purpose for failing to meet AAFCO minimum standards was its concern over pet obesity-dogs are too fat. There is considerable evidence that the nutritional requirements for dogs depends on the breed. Currently, the most basic standards-like amino acid requirements-are being challenged. Without NAC, there is a 68% reduction in the ability of the kidneys to do their job. With it, the loss of kidney function is only 29%. His frustrated owners had to come home at lunch to feed him. The problem is that fleas are only one of many things that can cause hair loss, which is usually accompanied by some sort of skin disorder. To date, he has been doing great, "He's on top of the world. She recommended that Harley be put on Life Extension Dog Mix (3 scoops), lipoic acid (500 mg/day), L-carnitine (1500 mg/day) and DHEA (100 mg). Bioavailability is a crucial issue. Despite promises of complete and balanced nutrition, many commercial pet foods could be making your animals sick. When the Science Diet® people went looking for a supplement that could help aging dogs stay alert, they focused on two important aspects of brain aging: energy and free radical damage. Our high-quality pet supplement for cats provides nutritional support to help keep your pet healthy. Provides a source of omega-3 and 6 fatty acids and joint-supporting glucosamine and chondroitin. That can add up, Linder says. Their requirement for meat protein is three times higher than omnivores like dogs. Arachidonic acid is absolutely critical for learning and remembering. 98% of our customers recommend us to family and friends. The brain is very susceptible to free radical damage because of its high fat content and high demand for energy. Barbiroli B, et al. The FDA has been receiving complaints from veterinarians that cats and dogs they are attempting to euthanize have developed a tolerance to the drug-it's taking more of the drug than it should to achieve euthanasia. They must have meat protein to maintain health. Generations of cats and dogs have been raised on "pet food." There is a general idea of what it takes to keep most cats and dogs from developing deficiency diseases such as rickets, but the idea that a bag or a can provides "complete and balanced nutrition" for your dog or your cat is not scientifically supported. Carnitine levels decline with age, and so does its transport. Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetylcarnitine and/or R-alpha-lipoic acid. Researchers at the University of Iowa have shown that when lipoic acid is added to cells from the aorta, it prevents the activation of NFkB, an inflammatory factor that makes blood cells stick together. Search Product Result. It appears that dogs prone to certain disorders also require certain dietary needs. Proc Natl Acad Sci 2002, 99:2356-61. JAVMA 1989, 195:583-90. This is what got the ire of Nutro and Kal Kan, both of which have lawsuits against P&G's Iams/Eukanuba for false advertising and misleading labeling. English setters, for example, can inherit a terrible disease called Batten disease which causes the brain to shrink. How could animals that had never had the drug before suddenly have tolerance to it? Bioavailability is how much of the food can actually be utilized by an animal for critical functions like the growth of cells. Similar findings are reported by French researchers when NAC is given as a pretreatment before experimental kidney damage in rats. The list of warning letters to pet food manufacturers since 1997 is very short. One way a manufacturer can prove that its dog food is "complete and balanced" is to feed the product to eight dogs for six months. The dog food the owners were feeding did not state that it met minimum nutritional requirements (AAFCO). Jack the cat was living the good life in Hollywood and seemed to have the world by the tail until the day he couldn't move and stopped eating. To save your recommendations, click the X in the upper right corner and then click Print or Email. By using Supplement Guide you understand that recommendations are in no way intended as a substitute for medical counseling and neither the publisher nor the authors have liability or responsibility to any person or entity receiving or using this information. Promotes heart health & healthy brain function. For more on the American Association of Feed Control Officers (AAFCO), see http://www.aafco.org. Any animal not responding to nutritional therapy should be seen by a licensed, competent veterinarian. Cats are strict carnivores. Information on homemade pet food can be found in Food Pets Die For; Let's Cook for Our Cat (1995); Dr. Pitcairn's Complete Guide to Natural Health for Dogs & Cats. Sousa CA, et al. Hagen TM, et al. Premium Pet Food Shop. These statements have not been evaluated by the Food and Drug Administration. It is blended with a vitamin mix, doused with flavoring and coloring to mask the gray color, put into a bag, box or can, labeled and sold. How much of what walks into a veterinarian's office is the result of poor nutrition? The letters were sent to Iams regarding Iams/Eukanuba dog food. Vet Microbiol 2001, 79:183-9. J Cereb Blood Flow Metab 1995, 15:624-30. In one recent study, researchers in Italy demonstrated that NAC normalizes creatinine levels in rodents with kidney failure. More information at www.ConsumerLab.com/survey. Walmart has all the top brands that your dog is looking for! Besides high-quality commercial foods that are nutrient-enriched, food supplements are the best way to ensure your pets are getting all the vitamins and minerals they need to live long, healthy lives. It is widely accepted in the scientific community that the definition of "complete and balanced" nutrition for dogs and cats is unknown. DHEA (dehydroepiandrosterone), for example, is a hormone secreted by the adrenal glands that declines drastically with age. Life Extension does not provide medical advice, diagnosis, or treatment. Free radicals, in turn, damage mitochondrial DNA. Feeding amounts were reduced 25%. Maintaining weight is a critical issue for AAFCO-approved pet food. The industry has contributed substantially to understanding the nutritional requirements of our "best friends." Individual results are not guaranteed and results may vary. One of the benefits of lowering blood sugar is that it reduces the risk of heart attack. This points out the importance of finding the root cause of a persistent problem. What about the Food and Drug? Enter your email address if you would like your recommendation emailed to you. (For the most current description of the pet food manufacturing process visit: www.petfoodinstitute.org ) Pet food is He told us that the agency hadn't found what's causing the problem. "Look Inside" a Rendering Plant, summer 1996. A bowl of chicken feet does not provide the same nutrition as a bowl of chicken thighs. Eur J Pharmacol 1994, 266:291-300. Am J Physiol Regul Integr Comp Physiol 2001, 281:R730-7. After examining the little terrier mix, the vet gave his diagnosis: arthritis. Hagen TM, et al. In another report, researchers found that lipoic acid actually restores critical nerve factors that are lost in diabetes. Her caretaker noticed that Cleo was hypersensitive to sound and light. "Flea allergy" or "food allergy" is a common diagnosis for animals loosing their hair. As great as it was to get the old mice up and going again, their increased energy came with a price: a 30% increase in free radicals. For a brief report of the study, see http://www.fda.gov/cvm. Eur J Paediatr Neurol 2001, 5 Suppl A:151-6. The first ingredient in quality pet food is meat. It's quick, it's easy, but is it really cheap? Expect to pay roughly $0.65 to $1 per pound. Additionally, lipoic acid can chelate iron and other metals, keeping them from fueling free radical chain reactions. Recommendation was sent to {{vm.model.email}}. Dogs are omnivores, able to utilize both animal and plant proteins. Our pet supplements contain ingredients that are held to the same standards as the rest of our products. It was five long days until the results came back. There are other methods to protect the brain as well. Ann Martin looked into the pet food industry after her own dog almost died from contaminated commercial dog food. Commercial pet food is the fast food of the animal world. Kittleson MD, et al. Gotz ME, et al. Protection of vital organs with antioxidants and amino acids, immune enhancement, longevity and the prevention of cancer are best achieved for our "best friends" by a high-quality diet and scientifically-proven supplements. A postsynaptic transient K(+) current modulated by arachidonic acid regulates synaptic integration and threshold for LTP induction in hippocampal pyramidal cells. In this study, the lean dogs lived on average 18-24 months longer than their littermates who ate more over their entire lives. Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. So how can you be sure that you are giving your pet premium nutrition? When Procter & Gamble bought Iams and Eukanuba, it changed the formula of the dog foods to a cheaper recipe. Hounsom L, et al. And although cats can't convert beta-carotene to vitamin A, they can use it to enhance their immune systems. It was the first time in months Harley had "acted like a dog." Researchers were able to correlate increased activity with increased energy production in the animals' mitochondria. Taste of the Wild is available for sale at major online retailers as well as local pet food stores. They had swollen lymph nodes and, worst of all, they had scaly, crusting areas where their fur was falling out. Hello, I make homemade dog food (moist) with natural ingredients and will want to go commercial,what natural preservatives can I use to extend its shelf life? Two cats put on the same commercial cat food may respond very differently. The dogs were depressed and lethargic. The veterinarian didn't have much hope, but offered to do surgery to clear any potential blockage and get a better grip on the situation. Greene EL, et al. Out went the meat, in went "by-product meal" (rendering plant product). Head E, et al. Oxidative stress participates in the breakdown of neuronal phenotype in experimental diabetic neuropathy. "She's doing great," said Charlene. Commercial pet food made with human-grade meat is available online. There is, however, a series of letters to Iams, a pet food company, that look a lot like warning letters, but aren't according to the FDA. The research on what NAC can do for the kidney (and the liver) is scientifically well-documented. Our Dog Mix helps protect and maintain your pet’s health. A critical evaluation. Lipoic acid has multiple actions. Jack's owner agreed, and a biopsy was taken during the procedure. For example, studies have shown that if an animal is given vitamin E and other antioxidants before it undergoes physical trauma, it is more likely to survive. It works much better when it's injected, but oral lipoic acid can drop blood sugar as well. Storing them on the shelf for an extended period of time, has negative effects on their flavour, aroma, texture and nutrients. They want to keep dangerous supplements out of pet food, but meanwhile, what's being kept in pet food? Proc Natl Acad Sci 2002, 99:1870-5. Millions of animals and their owners are relying on the promise that commercial pet food is "complete nutrition." Completely balanced diet containing highly digestible meat proteins. Neglecting canine dental care Periodontal disease (gum disease), is a common problem in dogs. No problem, right? Free Radic Biol Med 2001, 31:125-35. Mimi … Am J Physiol 1997, 272(3 Pt 2):F292-8. Carnitine is an amino acid that has a special role in energy production. McGahon BM, et al. NaSure 554. It could be a lot of chicken feet or a few chicken feathers-not even the company that makes it can tell you what's in a can, box or bag of commercial dog or cat food. Instead, he focused on Cleo's anxiety, and put her on a new supplement known as L-theanine. For dogs weighing 20-30 pounds, mix one scoop a day into your pet’s food or a treat. Turkey & Shrimpin Broth. People with kidney disease have depleted levels of DHEA. Is adequate nutrition what it takes to keep an animal from developing obvious deficiency diseases, such as soft bones? Propylene glycol, ethoxyquin, BHT, colorings and flavorings are potentially toxic when ingested repeatedly. Vitamin C plus ultra-absorbable quercetin for immune support. And while they appear to be similar to those set by the National Research Council (NRC)-the organization that sets RDAs for humans-they are not. As the American Humane Society reports, veterinarians estimate that 85 percent of dogs over five years of age suffer from the condition, which develops after food and bacteria collect along the gum line and form plaque in a dog’s mouth. For years nobody paid much attention to the diets of their cats and dogs. The question is, are these products providing enough quality nutrients. A few years? Neuroscience 1999, 94:305-14. She seemed to have nervous energy but no real energy. The American Association of Feed Control Officers (AAFCO) is responsible for the words "complete and balanced nutrition" on commercial pet food. A class-action suit on behalf of consumers has just been settled by the California firm of Wasserman, Comden, Casselman & Pearson. 68. Shop nutritional diet options including raw diet dog foods, gluten free, all natural, with-grain, as well as grain-free options. Another cause of hair loss is poor nutrition. J Nutr 2000, 130:2322-25. Please refer to the best before date stamped on the bottom of all canned products. Just like human beings, dogs need carbohydrates, fats, proteins, vitamins, minerals and water in a balanced diet to stay healthy. Dog Mix contains significant amounts of high-grade nutrients usually reserved for the most expensive human supplements. The company did not explain why it didn't increase the nutrients to make up for the caloric loss, nor indicate on the label that Iams is a diet food. Effect of lipoic acid on redox state of coenzyme Q in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and diethyldithiocarbamate. A month later, Jack's blood tests were normal. These associations may not be true for all individuals and are not based on specific product brands or formulations. Gigi was only five, but already she was getting the signs of old age. These are only some of the ways our "best friends" can benefit from the same high-quality nutrients that protect us. An ultrasound showed bloated, water-logged kidneys. His blood sugar dropped about 70%. Within a week, Gigi stopped limping, and Bill no longer had to help her into the car. So why didn't the food meet AAFCO standards? First shipment within 1 business day with. Assessment of the nutritional adequacy of pet foods through the life cycle. We've analyzed cost per pound, as dog foods can come in a range of bag sizes. Chicken, beef, turkey or other meat listed as the first or only ingredient indicates that the food is the highest quality commercial pet food you can buy. Morris JG, et al. Moreover, not only did the lean dogs live longer, they were healthier for longer as well – being lean also postponed the symptoms of many chronic disease processes such as arthritis. Some manufacturers even go so far as to warn people not to feed their animal(s) genuine food-only their products-as if it would be dangerous to feed little Fluffy meat and vegetables. Jack's owner refused to give up, however, and took his faithful friend to another vet for a second opinion. Life Extension Animals Case StudiesBy Terri Mitchell. Do not purchase if outer seal is broken or damaged. It's the only way to determine whether an animal is getting enough nutrients under current AAFCO testing guidelines. Memory was enhanced, and when the researchers looked at the hippocampus-a brain structure having to do with memory-they found that the combination of L-carnitine and lipoic acid actually kept the mitochondria from aging. ** This supplement should be taken in conjunction with a healthy diet and regular exercise program. That includes our furry friends. In fact, they were grocery store pet food with fancy labels. Buy the selected items together. High-quality protein is crucial for the health of dogs and cats. But the public record doesn't support that claim very well. NAC is strong medicine for the kidneys. Neuroprotection by the metabolic antioxidant alpha-lipoic acid. They immediately put Gigi onLife Extension Dog Mix (two scoops), MSM (500 mg/day) and glucosamine/chondroitin (900 mg/day). When the same researchers added lipoic acid to the L-carnitine supplements, oxidative stress was reduced to the level of youngsters and physical activity was even greater than that achieved with lipoic acid alone. He continued to vomit for several days (a side effect of kidney failure), but two weeks from the date of surgery, his BUN had dropped from 152mg/dl to 45.6mg/dl and he was up and around. Some argue that cats and dogs do not need to eat filet mignon. The little dog belonging to Lynne and Frank Burger scratched at her back constantly, but nothing they did seemed to help. What works for a labrador retriever may not be right for a greyhound. With top dog food brands you trust like, you'll find a wide variety of healthy dog food with flavors and food toppers to satisfy even the pickiest of eaters. But a lot of dog food isn’t designed with the optimal nutrients that they need to stay healthy. It enhances "nerve conduction velocity" and blood flow, and reverses blood vessel constriction. By chance, Mimi McClelland met a person familiar with Life Extension products. Liu J, et al. Effect of N-acetylcysteine on gentamicin-mediated nephropathy in rats. Copyright© 2021 Life Extension. By chance, Mimi McClelland met a person familiar with Life Extension products. Filling that need, the pet food industry has grown tremendously over the years. His blood sugar was on a roller-coaster ride, soaring then falling. After April 1, 2010, the unopened bag of pet food should be discarded. AAFCO is concerned with issues involving animal feed, and it advises the FDA and USDA on such matters. A third study confirms that an infusion of NAC before and after experimental kidney damage doubles the kidney filtration rate. Because trends in pet food are closely aligned to those in human food, natural shelf life solutions are preferred by certain … Nutritional and herbal products may vary widely in ingredient purity, concentration, and combinations, which may affect people differently. Consult your doctor, pharmacist, or other professional for any health problem and before adding supplements to your self-care practices or discontinuing any prescribed medications. Our Super-Absorbable CoQ10 (Ubiquinone) with d-Limonene supports heart and brain health with the added absorbable power of limonene. In a study from Purdue University, 100 mg/kg of DHEA a day given as a supplement for seven months to elderly dogs reduced the percentage of brain cells with extensive DNA damage by 42%. Brands include Wysong, Wellness, PetGuard and Active Life. Research shows that DHEA and NAC probably work synergistically, which is why they were given together. An 80 pound dog could, then, get about 160 mcg of pentobarbital a day. Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Life Extension. Neurobiol Aging 1999, 20:655-64. Here in the U.S., it's available as a supplement. JAVMA 1988, 192:676-80. The laboratory test results were grim. Health Extension Grain-Free New York Style Beef Recipe Canned Dog Food, 12.5-oz, case of 12 $30.48 Autoship & Save $32.08 $35.98 In Germany it is prescribed as a drug to people with diabetes. Ships from and sold by Amazon.com. Our Dog Mix supplements your dog’s diet with nutrients to help protect and maintain their overall health. Cameron NE, et al. That's true, but here is the problem. It combines a potent 300 mg of NIAGEN® nicotinamide riboside with trans-resveratrol in every dose. Theanine is a unique amino acid extracted from tea that has an anti-anxiety effect. 40 years of research dedicated to bringing you premium, scientifically-validated formulations. Cleo was sent home with a dose of 100 mg twice a day. Our Best in Class formula for digestive probiotic benefits. Ratings based on results of the 2021 and earlier ConsumerLab.com surveys of supplement users. But despite changing from a rice-and-lamb dog food from the grocery to a higher-grade dry food product, Harley's symptoms did not improve. Health Extension Original Dog Food. However, two weeks later, Harley's blood sugar again soared when his owners were away. All natural pet food infused with botanical herbs, learn to let the body heal itself. One additive that neither the FDA nor the AAFCO appears to be worried about is pentobarbital, an anesthetic commonly used by veterinarians to euthanize cats and dogs. You should not stop taking any medication without first consulting your physician. The dogs were depressed and lethargic. Mutat Res 2001, 480-81:153-62.Scott BC, et al. Refrigerate after opening. Everybody has nutritional needs, including your cat. Her caretaker called four days later, saying that not only was the dog cured, but that her husband was going to try theanine for his sleep problems. Evaluation of the components of a commercial probiotic in gnotobiotic mice experimentally challenged with Salmonella enterica subsp enterica ser Typhimurium. Maia OB, et al. Meat by-products is the next grade down. Pets are often considered family members deserving special attention. Maybe it's time to question whether your idea of "complete and balanced nutrition" is the same as whoever put those words on the label. Metabolism 2001, 50:868-75. Everything seemed fine until the day the dog passed out. ", Who created these standards? NAD+ Cell Regenerator™ and Resveratrol is our Best in Class formula for energy support. About half his body mass had disappeared. The information presented in Supplement Guide is for informational purposes only and should not be considered medical advice. Its antioxidant action may account for DHEA's ability to protect these vital cells. If you keep your dog healthy with regular walks and visits to the vet it can help give them a long, happy life. Life Extension Dog Mix - 3.52 oz (100 g) $ 12.75 : Ark Naturals Breath-less Brushless Toothpaste - Mini 4 oz (113 g) (1) $ 6.99 ... procedures or other items sold on or through this website have not been evaluated by eVitamins or by the United States Food and Drug Administration. Likewise, if a cat or dog gets high levels of taurine and L-carnitine in its diet, it is less likely to get an enlarged heart (cardiomyopathy). On one level, it restores and maintains other antioxidants including vitamins C and E, and the natural antioxidant, glutathione, which is diminished in the brains of elderly dogs. Life Extension is proud to be recognized as the #1 Catalog/Internet Merchant — 6 Time Winner.†. Just two scoops per day provide the vitamins your pet needs to stay healthy and strong. Parker CR, et al. Things were not looking good for Harley. There are none. Carnitine greatly reduced cognitive decline, and the combination reduced brain atrophy and extended lifespan 10%. So how is it that a manufacturer can claim "complete and balance?" NAC is a form of the amino acid, cysteine, with multiple kidney-protective actions. The report showed that Jack's kidneys were inflammed for no apparent reason. Little grains created by the immune system were filling up his kidneys, blocking the delicate filtering system. So they may benefit from certain supplemental nutrients. They got the scraps off the table, or the mice from the barn and that was about it. It is required for the transport of fatty acids into the mitochondria for the generation of metabolic energy. In a stunning report that was published in the Proceedings of the National Academy of Science, researchers at the University of California at Berkeley showed that elderly rats given L-carnitine doubled their activity to a level approaching that of young rats. A small percentage of dogs can go on to develop an Alzheimer's-like condition. It supports normal energy levels and healthy body composition and is important for heart health.1,2 Lipoic acid also provides mitochondrial support and may promote healthy brain aging in dogs.3 Vitamin E also has been shown to be important for physically active dogs’ health.4. Gigi was limping when caretakers, Bill and Charlene Baird, took her to the vet. The Nature of Animal Healing. A glimpse behind the scenes, however, reveals that there is little science behind commercial pet food. This item: Life Extension Dog Mix Powder, 100-Grams (01931) $12.75 ( $3.62 / 1 Ounce) In Stock. Free Radic Res 1994, 20:119-33. The brand makes both wet and dry food, as well as food for many stages of a dog’s life: puppy, adult, senior, and pregnant/nursing dogs. Mazzon E, et al. The localization of DHEA sulfotransferase in steroidogenic and steroid metabolizing tissues of the adult rhesus macaque monkey.

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